FeraSpin nanoparticle MRI reagent
April
18
2012

FeraSpin™ is a unique family of size-selected iron oxide nanoparticles for use in pre-clinical MRI.
FeraSpin is very well tolerated and has excellent MR contrast efficacy in T1-weighted or T2/T2*-weighted imaging.

FeraSpin Ris a super-paramagnetic iron oxide nanoparticle MRI agent for T2/T2*-weighted liver imaging. FeraSpin R has a large average particle size as well as a broad size distribution and is rapidly taken up by macrophages in liver and spleen.

FeraSpin XSis an ultra-small super-paramagnetic iron oxide nanoparticle agent for MR angiography (MRI). It has been size-selected from FeraSpin R and is also part of the FeraSpin Series presented below. It has the longest circulation time of the whole FeraSpin product family and can be imaged by both T1 (positive contrast) and T2/T2*-weighted sequences.

The FeraSpin Seriesis derived from FeraSpin R and encompasses six size-selected nanoparticulate agents with well-defined particle sizes from 10 to 100 nm. The range includes FeraSpin XS, FeraSpin S, FeraSpin M, FeraSpin L, FeraSpin XL, and FeraSpin XXL. The identical chemical composition and ultra-narrow size distribution of these particle fractions allows for fine-tuning of the pharmacologic profile applicable to your specific application - from long circulation in the blood pool to rapid accumulation in the reticuloendothelial system (RES) of liver and spleen. FeraSpin nanoparticles are very well suited for sequence development, MR physics and nanoparticle physiology studies.

Product

Applications

order no.

FeraSpin R

Small animal MRI of the liver and spleen using iron oxide nanoparticles

130-095-138
130-095-139

 

FeraSpin™ Series XS-XXL, MRI contrast agents

Product

Applications

order no.

     

FeraSpin XS

Small animal MRI using iron oxide nanoparticles of highly defined size

130-095-140
130-095-141

FeraSpin S

Small animal MRI using iron oxide nanoparticles of highly defined size

130-095-166
130-095-167

FeraSpin M

Small animal MRI using iron oxide nanoparticles of highly defined size

130-095-168
130-095-169

FeraSpin L

Small animal MRI using iron oxide nanoparticles of highly defined size

130-095-170
130-095-171

FeraSpin XL

Small animal MRI using iron oxide nanoparticles of highly defined size

130-095-172
130-095-173

 

 

FeraSpin XXL

Small animal MRI using  iron oxide nanoparticles of highly defined size

130-095-174
130-095-175